Read 42 times since Wednesday, November 23, 2011
Randomization during a clinical trial is a process of assigning the research volunteers not by choice but by chance in a controlled group during Phase II and III of the trial or investigational group. During the process, all the participants have equal chance of getting the new innovation being studied by mixing them with the investigational group or if they will be joining the controlled group.
The main purpose of randomization is to have a result that is based on generalized characteristics of the participants such as gender, age and some of the factors that will affect the disease that is being studied. When the clinical trial commences, the two groups are mostly alike and by the end of the trial, if one of the group give positive result, then the research group can now conclude that one of the interventions is far better than the other one. Randomization is considered as the most reliable and unbiased way of determining if the new medical intervention is successful.
Randomization is done on the research participants during the research studies so that it will give them a strong result on their research study. This will prevent the research studies from being bias on the participants for this might affect the results of the research studies. The intention of randomization is to save the doctors and the participants from selecting their own group that might influence and give biased opinion or select their own group.
Once the clinical trials undergo a randomized trial, the doctors involve in the research will not give false hope to the participants that have the disease wherein the drug is intended. The participants on the other hand will not be overly confident that the new drug will cure them from the illness. Once the research study is not randomized, there is a great chance of misconception on the drug as being effective than what it should really be. This is why randomized is practiced, to prevent from bias conclusion.
To help prevent from giving a bias opinion, research studies are "blinded" or "masked". These are divided into two, the first one is the single-blinded trial wherein the participants do not have any knowledge of the group they are involved not do they have any knowledge what kind on intervention they are receiving. The second is the double-blinded trial is a method wherein both the participants and the investigator do not know what group they are assigned. Both of this will give the true conclusion but this method is not used on new treatments but only used in the study of cancer prevention. For more information about clinical trials be sure to check with a verified, governemt approved clinical trial company, http://trialfacts.com/au/
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